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Bendjelloul, Malik 'Searching for Sugar Man' director Benenson, Peter Who founded Amnesty International more than four decades ago Bennett, Bob Republican from Utah served 18 years in U. Bennett, Brooke Missing Vermont girl found dead Bennett, Estelle Member of The Ronettes Bennett, Richard Rodney British composer, pianist and arranger Bennett, Robert Served 18 years as a U. Bennett Jr. Bentsen, Lloyd Texan served in Congress for 28 years and as President Clinton's first treasury secretary Berenstain, Stan Who with his wife created the popular children's books about a loving furry family called the Berenstain Bears Bergen, Polly Actress starred in 'Cape Fear' Berger, Sandy Former U.

Bergesch, Bill Former Cincinnati Reds general manager Bergman, Ingmar Iconoclastic filmmaker widely regarded as one of the great masters of modern cinema Bergonzi, Carlo Italian tenor Berle, Milton The acerbic, cigar-smoking vaudevillian who eagerly embraced a new medium Bernstein, Harry Published his first book at age Berra, Carmen Wife of Yogi Berra Berrigan, Daniel Jesuit priest helped shape the course of the s anti-war movement Best, George One of the most dazzling players in soccer history Betbeze Fox, Yolande Miss America helped change beauty pageants Bey, Turhan Actor whose exotic good looks earned him the nickname of "Turkish Delight" Biggers, William Watts Co-creator of the cartoon "Underdog" Biggins, Robert J.

Biggs, Barton Former Morgan Stanley strategist warned of dot-com crash Bikel, Theodore Actor and singer known for "Fiddler on the Roof" Bilk, Acker Legendary jazz clarinetist Binchy, Maeve Beloved Irish novelist Bisher, Furman Famed Georgia sportswriter Bishop, Joey Comedian was the Rat Pack's last surviving member Bivins, Jimmy Hall of Fame boxer Black, Cilla Legendary TV presenter and singing star Black, Karen Actress appeared in more than movies Black, Linda C. Astrologer whose forecasts were read in newspapers across the world Blackwell, Unita Civil rights activist was advisor to seven presidents Blah, Moses Served as Liberia's president for two months Blair, Janet Vivacious actress appeared in several s musicals and comedies, then turned to television Blair II, W.

Bland, Bobby "Blue" Distinguished singer known as the "the Sinatra of the blues" Blank, Les Acclaimed documentary filmmaker Blankley, Tony Conservative author and commentator Blatnick, Jeff Olympic gold medal wrestler Blazonczyk, Eddie Grammy Award-winning polka great Blegvad, Erik Children's book artist Bleuel, Amy Advocate founded the suicide prevention initiative Project Semicolon Bley, Paul Canadian-born U. Bloomingdale, Betsy Fashion icon was known for her philanthropy Blosil, Michael year-old son of entertainer Marie Osmond Blount, Lisa Actor and Academy Award winning filmmaker Blue, Forrest Four-time Pro Bowl center Blumberg, Baruch S.

Shared the Nobel Prize for his discovery of the hepatitis B virus Blunk, Jonathan T. Bobek, Stjepan Yugoslav football legend Boerwinkle, Tom Former Chicago Bulls center Boggs, Grace Lee Longtime labor, civil rights activist Boggs, Lindy Former Louisiana Congresswoman Boggs, Thomas Hale Powerful Washington lobbyist and son of congressional royalty Bogle, Bob Lead guitarist and co-founder of the rock band The Ventures Boik, Alexander J.

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Bombing Victims, Brussels, Belgium, At least 23 people are dead after three explosions Bombing Victims, Kabul At least 28 killed in Afghanistan explosion Bond, Julian Lifelong civil rights activist Bond, Michael English children's author created the beloved Paddington Bear Bonds, Bobby One of the first major leaguers to blend home-run power with base-stealing speed Bonds, Judy Environmental activist was a vocal critic of mountaintop removal coal mining Boogaard, Derek One of hockey's most-feared enforcers One of the first black military aviators known as the Tuskegee Airmen Boone, Eunetta Showrunner who created "One on One" Booth, Adrian Film actress also threw pies with the Three Stooges Boothe, Powers Emmy-winning actor excelled in villain roles Borbon, Pedro Baseball player pitched 10 years for the Cincinnati Reds Borgnine, Ernest Screen star won the best-actor Oscar in Borislow, Dan The inventor of magicJack Bork, Robert H.

Famously unsuccessful Supreme Court nominee Boros, Steve Played a key role in one of baseball's most thrilling World Series moments Bose, Amar Founder and chairman of audio technology company Bose Corp Boston, Bernie Newspaper photographer best known for his iconic s picture of a Vietnam War protester Bottoms, Sam Actor had a small but memorable role in the s classic "Apocalypse Now" Bouchard, Emile Longtime Montreal Canadiens captain Boulez, Pierre World-renowned French classical music conductor Bowen, Otis R.

Former Indiana Governor and U. Health and Human Services Secretary Bowie, David Legendary British singer and boundary-breaking musician The first black managing editor of The New York Times Boyle, Patricia Former federal judge Boynton Robinson, Amelia U.


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Brady, James Former White House press secretary Brady, Sarah Kemp Gun control activist Braithwaite, E. Author penned novel "To Sir, With Love" that became a movie Brandt, Dr. Fredric Pioneering dermatologist, author and early proponent of Botox Brandt, Margit Fashion icon led international breakthroughs for Danish designs Branton, Leo Lawyer helped radical Angela Davis win sensational murder case Brashear, Carl M. First black U. Navy diver, portrayed in the film ''Men of Honor" Brasse, Wilhelm Auschwitz prisoner and photographer Brazda, Rudolf Last surviving person interned by Nazis because of his homosexuality Brazelton, Dr.

Brecker, Michael Versatile and influential tenor saxophonist won 11 Grammys Breed, MC Michigan rapper burst onto the national scene in Breen, Bobby Former child star best known in the s Breitbart, Andrew Conservative media publisher and activist Brennan, Eileen Actress starred in "Private Benjamin" Brenner, David Comedian, actor, author Briban, Roxana Romanian opera singer Bridges, Dorothy Matriarch of the acting family that includes sons Jeff and Beau Brillstein, Bernie Veteran Hollywood manager, producer and power broker Brinker, Norman Restaurant mogul who built casual dining empire Brinkman, Eddie Record-setting shortstop had a year career in the majors and coached the White Sox Brock, Mona Lee Counseled farmers in crisis Broder, David Pulitzer Prize-winning political reporter and columnist Brodeur, Denis Father of star goalie Martin Brodeur Broner, E.

Pioneering Jewish feminist writer Bronfman, Edgar M. Businessman, Jewish advocate Bronson, Charles Grim-faced tough guy made his mark with action films like the "Death Wish" series Brooks, Cedric Influential roots reggae musician Brooks, Herb Former Olympic hockey coach led U. Brooks, Martin Actor who played Dr. Brothers, Jim Kansas sculptor, whose works are at historical monuments around the country Brothers, Joyce Pop psychologist pioneered the television advice show Brotman, Jeff Costco chairman co-founded the warehouse retailer Browder, Kalief Teen who was jailed 3 years without trial, then freed Brown, Bonnie Member of country music vocal group the Browns Brown, Chris All-Star third baseman played six seasons in the majors in the s Brown, Chuck Musician widely acclaimed as the "Godfather of go-go" Brown, Cynthia Human Rights Watch activist Brown, Eric British pilot who flew more types of airplanes than anyone else in history Brown, Errol Hot Chocolate singer Brown, Gates Former Tigers outfielder Brown, Helen Gurley Legendary editor of Cosmopolitan magazine Brown, James The dynamic, pompadoured "Godfather of Soul" Brown, Joe L.

General manager helped Pittsburgh Pirates win 2 World Series titles Brown, Linda Student in the landmark Brown v. Board of Education U.

Brown, Marcia Award-winning children's book illustrator Brown, Michael Teenager was fatally shot by a police officer Brown, Nappy Blues singer climbed the Billboard charts with his gospel-influenced style Brown, Ruth Whose recordings shot her to rhythm-and-blues stardom in the s Brown, Vivian Famous San Francisco twin Naval Academy Brown, Wesley Oldest sitting U.

Brown, Willie Raiders legend helped lead the team to their first Super Bowl win Browne, Joy Nationally syndicated call-in talk show host Browne, Malcolm Photograper of Vietnamese burning monk Browne, Sylvia Popular psychic and author Browning, James The nation's longest-serving federal appellate judge Martini in the classic film "It's a Wonderful Life" Buchwald, Art Pulitzer Prize winning columnist chronicled the life and times of Washington Buck, Leslie Created the cardboard cup that became a pop-culture emblem of New York WWI veteran Buckley, William F.

Erudite Ivy Leaguer and conservative commentator Buffone, Doug Former Chicago Bears linebacker Building Explosion Victims, Harlem At least seven have died in a gas explosion Bumpers, Dale Former U.

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The molecular players in oocyte cortical tension as well as the consequences of aberrant tension have started to be uncovered as well. This function of myosin II Fig. Flies deficient in Moesin the only Drosophila ERM protein have abnormalities in oocyte cell shape, oocyte polarity, actin organization, and localization of certain maternal determinants such as Oskar and Staufen Jankovics et al.

It is interesting to note that radixin is among the most abundant mRNAs detected in mouse oocyte transcriptomes e. The discovery of the nearly 2. Mitotic cytokinesis that is producing symmetrically sized daughter cells appears to be exquisitely sensitive to pressure imbalances induced by mechanical stress. Our recent results Larson et al. An additional finding of this recent work on mammalian oocyte mechanics Larson et al. Spindles in ovulated eggs tend to be shorter and often with narrower poles as compared to the spindles in in vitro matured eggs, which are longer with broader poles Sanfins et al.

This will be an interesting area for future study with implications for cell biology as well as potentially for clinical practice in assisted reproductive technology clinics that use in vitro oocyte maturation methods. A question to be considered is if cortical tension in the egg could impact not just cytokinesis and polar body emission, but fertilization.

As noted, our work showed that the microvillar domain has lower tension than does the amicrovillar domain, and also that the early zygote has a higher tension level than does the unfertilized egg Larson et al. Based on this, high tension does not appear to be sufficient to make a membrane, either of the zygote or in the amicrovillar domain of an egg, impenetrable by sperm. In summary, cellular mechanics is returning to the forefront as a crucial subdiscipline in biology. This is underscored by the rich history of studying mechanics in early invertebrate embryos starting in the first part of the 20th century, which in turn provided a foundation for the more recent studies of mouse oocytes noted here Larson et al.

Taken together, the work suggests that the mechanical properties of the oocyte are critical for successful progression through cytokinesis, polar body emission, and spindle morphology, and more broadly raises the possibility that oocyte mechanics may prove to be a marker linked with egg health and quality. The full text of this article hosted at iucr. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account.

If the address matches an existing account you will receive an email with instructions to retrieve your username. Molecular Reproduction and Development. Review Article Free Access. Janice P. Wolfe St. Search for more papers by this author. Douglas N. Tools Request permission Export citation Add to favorites Track citation.

Share Give access Share full text access. Share full text access. Please review our Terms and Conditions of Use and check box below to share full-text version of article. Abstract Recent work shows that cytokinesis and other cellular morphogenesis events are tuned by an interplay among biochemical signals, cell shape, and cellular mechanics. Figure 1 Open in figure viewer PowerPoint. Figure 2 Open in figure viewer PowerPoint.